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1

Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: ex vivo and in vivo studies

WESSALE, Jerry L., ADLER, Andrew L., NOVOSAD, Eugene I., CALZADILLA, Samuel V., DAYTON, Brian D., MARSH, Kennan C., WINN, Martin, JAE, Hwan-Soo, GELDERN, Thomas W.von, OPGENORTH, Terry J., WU-WONG, J.

Journal:

Clinical Science

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

2

Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies

WU-WONG, J. Ruth, DIXON, Douglas B., CHIOU, William J., SORENSEN, Brian K., LIU, Gang, JAE, H.-S., TASKER, Andrew, GELDERN, Thomas W. Von, WINN, Martin, OPGENORTH, Terry J.

Journal:

Clinical Science

Year:

2002

Language:

english

File:

PDF, 120 KB

english, 2002

3

5-Membered ring heterocyclic carboxylic acids as angiotensin II antagonists

John Pratt, Hwan-Soo Jae, Saul Rosenberg, Ken Spina, Martin Winn, Steven Buckner, Eugene Novosad, Daniel Kerkman, Kazumi Shiosaki, Terry Opgenorth, Hohn DeBernardis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 254 KB

english, 1994

4

Bladder secretion of inhibitors of calcium oxalate crystal growth

Martin, Xavier, Opgenorth, Terry J, Werness, Peter G, Rundquist, Robert T, Romero, J Carlos, Smith, Lynwood H

Journal:

Kidney International

Year:

1985

Language:

english

File:

PDF, 378 KB

english, 1985

5

The renal action of atrial natriuretic peptide during control of glomerular filtration

Burnett, John C, Opgenorth, Terry J, Granger, Joey P

Journal:

Kidney International

Year:

1986

Language:

english

File:

PDF, 369 KB

english, 1986

6

Effect of ABT-627 (A-147627), a potent selective ETA receptor antagonist, on the cardiopulmonary profile of newborn lambs with surgically-induced diaphragmatic hernia

Mélanie Kavanagh, Bruno Battistini, Sonia Jean, Josiane Crochetière, Louis Fournier, Jerry Wessale, Terry J Opgenorth, Raymond Cloutier, Diane Major

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 231 KB

english, 2001

7

[3H]A-81988, a potent, selective, competitive antagonist radioligand for angiotensin AT1 receptors

Arthur A. Hancock, Bruce W. Surber, Gary Rotert, Samuel Thomas, Andrew S. Tasker, Bryan K. Sorensen, Alex D. Vodenlich, Terry J. Opgenorth, Daniel J. Kerkman, John F. DeBernardis

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 517 KB

english, 1994

8

ABT-627, an endothelin ETA receptor-selective antagonist, attenuates tactile allodynia in a diabetic rat model of neuropathic pain

Michael F Jarvis, Jerry L Wessale, Chang Z Zhu, James J Lynch III, Brian D Dayton, Samuel V Calzadilla, Robert J Padley, Terry J Opgenorth, Elizabeth A Kowaluk

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 237 KB

english, 2000

9

HPLC and PDMS analysis of cleavage products aid in the design of small, stable ANP analogues

EDWARD M. DEVINE JR., ALEXANDER M. BUKO, STEVEN P. CEPA, STEVEN K. DAVIDSEN, WILLIAM H. HOLLEMAN, CAROL A. MARSELLE, TERRY J. OPGENORTH, TODD W. ROCKWAY, THOMAS W. VON GELDERN

Journal:

Chemical Biology & Drug Design

Year:

1992

Language:

english

File:

PDF, 501 KB

english, 1992

10

ETAReceptor Blockade Potentiates the Bronchoconstrictor Response to ET-1 in the Guinea Pig Airway

James S. Polakowski, Terry J. Opgenorth, David M. Pollock

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 92 KB

english, 1996

11

Characterization of endothelin converting enzyme in rat lung

Jinshyun R. Wu-Wong, Gerald P. Budzik, Edward M. Devine, Terry J. Opgenorth

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 403 KB

english, 1990

12

Comparison of the hemodynamic effects of endothelin-1 and big endothelin-1 in the rat

David M. Pollock, Terry J. Opgenorth

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 318 KB

english, 1991

13

Rhamnose moiety of phosphoramidon is not required for in vivo inhibition of endothelin converting enzyme

David M. Pollock, Kazumi Shiosaki, Gerard M. Sullivan, Terry J. Opgenorth

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 298 KB

english, 1992

14

Effect of cell density on endothelin release from endothelial cells and phosphoramidon dependent inhibition

Rosemary Zaragoza, Gerald P. Budzik, Terry P. Dillon, Terry J. Opgenorth

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 504 KB

english, 1992

15

Atrial natriuretic factor and endothelm interactions in control of vascular tone

Terry J. Opgenorth, Eugene I. Novosad

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 754 KB

english, 1990

16

In vivo characterization of a phosphoramidon-sensitive endothelin-converting enzyme in the rat

David M. Pollock, Barbara J. Divish, Ivan Milicic, Eugene I. Novosad, Neal S. Burres, Terry J. Opgenorth

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 529 KB

english, 1993

17

Characterisation of functional endothelin receptors in the canine isolated perfused spleen

Dora M. Grassi-Kassisse, Renato Faro, Peter G. Withrington, Roberto Zatz, Terry J. Opgenorth, Edson Antunes, Gilberto De Nucci

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 658 KB

english, 1995

18

Endothelins and endothelin receptor antagonists: Binding to plasma proteins

Jinshyun R. Wu-Wong, William J. Chiou, Daniel J. Huffman, Martin Winn, Thomas W. von Geldern, Terry J. Opgenorth

Journal:

Year:

1996

Language:

english

File:

PDF, 709 KB

english, 1996

19

Metabolic responses with endothelin antagonism in a model of insulin resistance

Nathalie Berthiaume, Jerry L. Wessale, Terry J. Opgenorth, Bradley A. Zinker

Journal:

Year:

2005

Language:

english

File:

PDF, 137 KB

english, 2005

20

The effects of diminishing albumin binding to some Endothelin receptor antagonists

Bruce G. Szczepankiewicz, Radhika B. Bal, Thomas W. von Geldern, Jinshyun R. Wu-Wong, William J. Chiou, Douglas B. Dixon, Terry J. Opgenorth, Daniel J. Hoffman, Anthony J. Borre, Kennan C. Marsh, Bach

Journal:

Year:

1998

Language:

english

File:

PDF, 602 KB

english, 1998

21

Direct determination of endothelin receptor antagonist levels in plasma using a scintillation proximity assay

Brian D Dayton, William J. Chiou, Terry J. Opgenorth, Jinshyun R. Wu-Wong

Journal:

Year:

2000

Language:

english

File:

PDF, 694 KB

english, 2000

22

New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade

Joel B Nelson, Son H Nguyen, Jinshyun R Wu-Wong, Terry J Opgenorth, Douglas B Dixon, Leland W.K Chung, Nozomu Inoue

Journal:

Year:

1999

Language:

english

File:

PDF, 270 KB

english, 1999

23

ETA receptor-mediated responses to endothelin-1 and big endothelin-1 in the rat kidney

David M. Pollock, Terry J. Opgenorth

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 804 KB

english, 1994

24

Atrial natriuretic peptide (ANP) does not inhibit the basal vascular tone present in the in situ blood-perfused dog gracilis muscle

Richard E. Klabunde, Mary C. Helgren, Eugene I. Novosad, Terry J. Opgenorth

Journal:

Year:

1990

Language:

english

File:

PDF, 466 KB

english, 1990

25

Endothelin receptor antagonists exhibit diminishing potency following incubation with agonist

Jinshyun R. Wu-Wong, William J. Chiou, Kurt E. Naugles Jr., Terry J. Opgenorth

Journal:

Year:

1994

Language:

english

File:

PDF, 528 KB

english, 1994

26

Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production

Dale S. Edgerton, Peer B. Jacobson, Terry J. Opgenorth, Bradley Zinker, David Beno, Tom von Geldern, Lars Ohman, Melanie Scott, Doss Neal, Alan D. Cherrington

Journal:

Year:

2006

Language:

english

File:

PDF, 241 KB

english, 2006

27

Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance

Bradley Zinker, Amanda Mika, Phong Nguyen, Denise Wilcox, Lars Öhman, Thomas W. von Geldern, Terry Opgenorth, Peer Jacobson

Journal:

Year:

2007

Language:

english

File:

PDF, 287 KB

english, 2007

28

Role of endothelin ETA receptors in the hypertension produced by 4-day l-nitroarginine methyl ester and cyclosporine treatment

David M Pollock, James S Polakowski, Terry J Opgenorth, Jennifer S Pollock

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 256 KB

english, 1998

29

Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 5. Highly Selective, Potent, and Orally Active ET A Antagonists

Jae, Hwan-Soo, Winn, Martin, von Geldern, Thomas W., Sorensen, Bryan K., Chiou, William J., Nguyen, Bach, Marsh, Kennan C., Opgenorth, Terry J.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 104 KB

english, 2001

30

Azole Endothelin Antagonists. 2. Structure−Activity Studies

von Geldern, Thomas W., Kester, Jeffrey A., Bal, Radhika, Wu-Wong, Jinshyun R., Chiou, William, Dixon, Douglas B., Opgenorth, Terry J.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 380 KB

english, 1996

31

Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 2. Sulfonamide-Based ET A /ET B Mixed Antagonists

Jae, Hwan-Soo, Winn, Martin, Dixon, Douglas B., Marsh, Kennan C., Nguyen, Bach, Opgenorth, Terry J., von Geldern, Thomas W.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 337 KB

english, 1997

32

Endothelins in Canine Genitourinary Tissues

Langenstroer, Peter, Tang, Rui, Divish, Barbara, Opgenorth, Terry, Shapiro, Ellen, Lepor, Herbert

Journal:

The Journal of Urology

Year:

1997

Language:

english

File:

PDF, 1.16 MB

english, 1997

33

A familial risk of chronic renal failure among blacks on dialysis?

Ferguson, Rollington, Grim, Clarence E., Opgenorth, Terry J.

Journal:

Journal of Clinical Epidemiology

Year:

1988

Language:

english

File:

PDF, 688 KB

english, 1988

34

Potent and selective inhibitors of an aspartyl protease-like endothelin converting enzyme identified in rat lung

Shiosaki, Kazumi, Tasker, Andrew S., Sullivan, Gerard M., Sorensen, Bryan K., von Geldern, Thomas W., Wu-Wong, Jinshyun R., Marselle, Carol A., Opgenorth, Terry J.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.11 MB

english, 1993

35

Azole Endothelin Antagonists. 1. A Receptor Model Explains an Unusual Structure−Activity Profile

von Geldern, Thomas W., Hutchins, Charles, Kester, Jeffrey A., Wu-Wong, Jinshyun R., Chiou, William, Dixon, Douglas B., Opgenorth, Terry J.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 334 KB

english, 1996

36

2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ET A Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

Winn, Martin, von Geldern, Thomas W., Opgenorth, Terry J., Jae, Hwan-Soo, Tasker, Andrew S., Boyd, Steven A., Kester, Jeffrey A., Mantei, Robert A., Bal, Radhika, Sorensen, Bryan K., Wu-Wong, Jinshyun

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 402 KB

english, 1996

37

Design, Synthesis, and Activity of a Series of Pyrrolidine-3-carboxylic Acid-Based, Highly Specific, Orally Active ET B Antagonists Containing a Diphenylmethylamine Acetamide Side Chain

Liu, Gang, Kozmina, Natasha S., Winn, Martin, von Geldern, Thomas W., Chiou, William J., Dixon, Douglas B., Nguyen, Bach, Marsh, Kennan C., Opgenorth, Terry J.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 140 KB

english, 1999

38

Beneficial Effect of the ANF Analog A68828 on Recovery from Ischemic Acute Renal Failure

Pollock, David M., Opgenorth, Terry J.

Journal:

Year:

1992

Language:

english

File:

PDF, 429 KB

english, 1992

39

Atrial Natriuretic Peptides in the Treatment of Acute Renal Failure

Pollock, David M., Opgenorth, Terry J.

Journal:

Year:

1993

Language:

english

File:

PDF, 1024 KB

english, 1993

40

[Advances in Pharmacology] Volume 33 || Endothelin Receptor Antagonism

Opgenorth, Terry J.

Year:

1995

Language:

english

File:

PDF, 3.92 MB

english, 1995

41

‘Irreversible’ Endothelin-1 Binding Does Not Prohibit ABT-627 From Reversing Endothelin-1-Induced Effects

Chiou, William J., Wessale, Jerry L., Geldern, Thomas von, Opgenorth, Terry J., Wu-Wong, Jinshyun R.

Journal:

Journal of Cardiovascular Pharmacology

Year:

2000

Language:

english

File:

PDF, 67 KB

english, 2000

42

Stimulation of Endogenous Endothelin Release in the Anesthetized Rat

Pollock, David M., Divish, Barbara J., Opgenorth, Terry J.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 2.26 MB

1993

43

Increased Susceptibility to Deoxycorticosterone Acetate-Salt-Induced Hypertension in Endothelin-B-Receptor-Deficient Rats

Matsumura, Yasuo, Kuro, Toshihiko, Kobayashi, Yutaka, Konishi, Fumiko, Takaoka, Masanori, Wessale, Jerry L., Opgenorth, Terry J., Gariepy, Cheryl E., Yanagisawa, Masashi

Journal:

Journal of Cardiovascular Pharmacology

Year:

2000

File:

PDF, 1.81 MB

2000

44

Increased Susceptibility to Deoxycorticosterone Acetate-Salt-Induced Hypertension in Endothelin-B-Receptor-Deficient Rats

Matsumura, Yasuo, Kuro, Toshihiko, Kobayashi, Yutaka, Konishi, Fumiko, Takaoka, Masanori, Wessale, Jerry L., Opgenorth, Terry J., Gariepy, Cheryl E., Yanagisawa, Masashi

Journal:

Journal of Cardiovascular Pharmacology

Year:

2000

File:

PDF, 1.81 MB

2000

45

Effect of the Endothelin ET A Receptor Antagonist, BQ-123, on Pressor Responses to Endothelin Family Peptides

Pollock, David M., Divish, Barbara J., Polakowski, James S., Opgenorth, Terry J.

Journal:

Year:

1993

Language:

english

File:

PDF, 534 KB

english, 1993

46

Surgery and Plasma Infusion Increase Circulating Immunoreactive Endothelin in the Anesthetized Rat

Pollock, David M., Divish, Barbara J., Opgenorth, Terry J.

Journal:

Year:

1993

Language:

english

File:

PDF, 478 KB

english, 1993

47

Perioperative Plasma Endothelin-1 and Big Endothelin-1 Concentrations in Elderly Patients Undergoing Major Surgical Procedures

Nelson, Joel B., Opgenorth, Terry J., Fleisher, Lee A., Frank, Steven M.

Journal:

Anesthesia & Analgesia

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

48

Dissociation Characteristics of Endothelin ETA Receptor Agonists and Antagonists

Wu-Wong, Jinshyun R., Chiou, William J., Dixon, Doug B., Opgenorth, Terry J.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1995

File:

PDF, 409 KB

1995

49

Increased Susceptibility to Deoxycorticosterone Acetate-Salt-Induced Hypertension in Endothelin-B-Receptor-Deficient Rats

Matsumura, Yasuo, Kuro, Toshihiko, Kobayashi, Yutaka, Konishi, Fumiko, Takaoka, Masanori, Wessale, Jerry L., Opgenorth, Terry J., Gariepy, Cheryl E., Yanagisawa, Masashi

Journal:

Journal of Cardiovascular Pharmacology

Year:

2000

Language:

english

File:

PDF, 26 KB

english, 2000

50

Prolonged Treatment by Phosphoramidon Modulates the Number of Endothelin Receptors in Cultured Swiss 3T3 Fibroblasts

Wu-Wong, Jinshyun R., Chiou, William J., Opgenorth, Terry J.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 2.43 MB

1993